Jornada 1
| 22 Jul 21 |  Querétaro |
0 - 1 |  América |
1 |
| 23 Jul 21 |  Necaxa |
3 - 0 |  Santos |
... |
| 23 Jul 21 |  Juárez |
0 - 1 |  Toluca |
... |
| 24 Jul 21 |  Chivas |
1 - 5 |  Atl. Luis |
... |
| 24 Jul 21 |  Pachuca |
0 - 1 |  León |
... |
| 25 Jul 21 |  Pumas UNAM |
1 - 0 |  Atlas |
... |
| 24 Jul 21 |  Monterrey |
4 - 1 |  Puebla |
... |
| 26 Jul 21 |  Tijuana |
1 - 1 |  Tigres UANL |
... |
| 26 Jul 21 |  Cruz Azul |
1 - 1 |  Mazatlán |
... |
Jornada 2
| 30 Jul 21 | Puebla |
3 - 1 | Chivas |
... |
| 30 Jul 21 | Mazatlán |
1 - 1 | Pachuca |
... |
| 31 Jul 21 | América |
3 - 1 | Necaxa |
... |
| 31 Jul 21 | Atlas |
2 - 1 | Juárez |
... |
| 31 Jul 21 | León |
2 - 1 | Tijuana |
... |
| 31 Jul 21 | Monterrey |
3 - 1 | Pumas UNAM |
... |
| 01 Ago 21 | Toluca |
2 - 0 | Tigres UANL |
... |
| 01 Ago 21 | Santos |
1 - 0 | Cruz Azul |
... |
| 02 Ago 21 | Atl. Luis |
0 - 2 | Querétaro |
... |
Jornada 3
| 05 Ago 21 | Querétaro |
1 - 0 | León |
... |
| 06 Ago 21 | Necaxa |
1 - 0 | Cruz Azul |
... |
| 06 Ago 21 | Mazatlán |
1 - 4 | Monterrey |
2 |
| 07 Ago 21 | Tijuana |
1 - 0 | Toluca |
... |
| 07 Ago 21 | América |
3 - 3 | Puebla |
... |
| 07 Ago 21 | Chivas |
0 - 0 | Juárez |
... |
| 07 Ago 21 | Tigres UANL |
1 - 1 | Santos |
... |
| 08 Ago 21 | Pumas UNAM |
5 - 3 | Atl. Luis |
... |
| 09 Ago 21 | Pachuca |
1 - 1 | Atlas |
... |
Jornada 4
| 12 Ago 21 | Atl. Luis |
1 - 2 | Necaxa |
... |
| 13 Ago 21 | Puebla |
2 - 1 | Tigres UANL |
... |
| 13 Ago 21 | Juárez |
1 - 3 | Tijuana |
... |
| 14 Ago 21 | Cruz Azul |
2 - 2 | Toluca |
... |
| 14 Ago 21 | León |
1 - 0 | Mazatlán |
... |
| 14 Ago 21 | Monterrey |
1 - 1 | Pachuca |
... |
| 14 Ago 21 | Pumas UNAM |
1 - 4 | Querétaro |
... |
| 15 Ago 21 | Atlas |
0 - 2 | América |
... |
| 15 Ago 21 | Santos |
1 - 2 | Chivas |
... |
Jornada 5
| 17 Ago 21 | Tigres UANL |
3 - 0 | Querétaro |
... |
| 17 Ago 21 | Toluca |
3 - 1 | Mazatlán |
... |
| 17 Ago 21 | Necaxa |
1 - 1 | Pumas UNAM |
... |
| 18 Ago 21 | Tijuana |
3 - 0 | Puebla |
... |
| 18 Ago 21 | Cruz Azul |
2 - 1 | Monterrey |
... |
| 18 Ago 21 | Chivas |
1 - 2 | León |
2 |
| 18 Ago 21 | Juárez |
1 - 1 | América |
... |
| 18 Ago 21 | Santos |
3 - 1 | Atlas |
... |
| 03 Nov 21 | Pachuca |
1 - 3 | Atl. Luis |
... |
Jornada 6
| 20 Ago 21 | Mazatlán |
3 - 2 | Tigres UANL |
... |
| 21 Ago 21 | Atlas |
1 - 2 | Toluca |
... |
| 21 Ago 21 | León |
1 - 1 | Santos |
... |
| 21 Ago 21 | Monterrey |
1 - 1 | Chivas |
... |
| 21 Ago 21 | Atl. Luis |
0 - 0 | Cruz Azul |
... |
| 22 Ago 21 | América |
1 - 1 | Tijuana |
... |
| 22 Ago 21 | Necaxa |
4 - 1 | Juárez |
... |
| 22 Ago 21 | Querétaro |
1 - 2 | Pachuca |
... |
| 22 Ago 21 | Pumas UNAM |
1 - 3 | Puebla |
... |
Jornada 7
| 27 Ago 21 | Puebla |
0 - 1 | Querétaro |
... |
| 27 Ago 21 | Mazatlán |
3 - 1 | Atl. Luis |
... |
| 28 Ago 21 | Tijuana |
1 - 0 | Monterrey |
... |
| 28 Ago 21 | León |
2 - 2 | América |
... |
| 28 Ago 21 | Tigres UANL |
0 - 1 | Atlas |
... |
| 28 Ago 21 | Chivas |
2 - 0 | Necaxa |
... |
| 29 Ago 21 | Cruz Azul |
0 - 0 | Pachuca |
... |
| 29 Ago 21 | Toluca |
2 - 2 | Pumas UNAM |
... |
| 29 Ago 21 | Santos |
3 - 1 | Juárez |
... |
Jornada 8
| 10 Sep 21 | Puebla |
2 - 2 | Atl. Luis |
... |
| 10 Sep 21 | Juárez |
0 - 1 | Cruz Azul |
... |
| 11 Sep 21 | Tijuana |
2 - 2 | Santos |
... |
| 11 Sep 21 | América |
3 - 0 | Mazatlán |
... |
| 11 Sep 21 | Atlas |
3 - 1 | Monterrey |
... |
| 11 Sep 21 | Tigres UANL |
2 - 0 | León |
... |
| 12 Sep 21 | Querétaro |
2 - 2 | Necaxa |
... |
| 12 Sep 21 | Pumas UNAM |
1 - 2 | Chivas |
... |
| 13 Sep 21 | Pachuca |
2 - 0 | Toluca |
3 |
Jornada 9
| 16 Sep 21 | Atl. Luis |
3 - 0 | Tijuana |
... |
| 17 Sep 21 | Necaxa |
1 - 2 | Atlas |
... |
| 18 Sep 21 | Mazatlán |
2 - 1 | Pumas UNAM |
... |
| 18 Sep 21 | Toluca |
3 - 1 | América |
... |
| 18 Sep 21 | León |
2 - 0 | Juárez |
... |
| 18 Sep 21 | Chivas |
1 - 2 | Pachuca |
... |
| 19 Sep 21 | Cruz Azul |
1 - 1 | Querétaro |
... |
| 19 Sep 21 | Monterrey |
0 - 1 | Tigres UANL |
... |
| 19 Sep 21 | Santos |
4 - 2 | Puebla |
... |
Jornada 10
| 23 Sep 21 | Pachuca |
1 - 1 | Necaxa |
1 |
| 24 Sep 21 | Puebla |
0 - 0 | Cruz Azul |
1 |
| 24 Sep 21 | Juárez |
1 - 1 | Querétaro |
... |
| 25 Sep 21 | Tijuana |
3 - 5 | Mazatlán |
... |
| 25 Sep 21 | Atlas |
2 - 1 | León |
... |
| 25 Sep 21 | América |
1 - 3 | Chivas |
... |
| 25 Sep 21 | Tigres UANL |
2 - 1 | Pumas UNAM |
1 |
| 26 Sep 21 | Toluca |
2 - 0 | Atl. Luis |
... |
| 26 Sep 21 | Santos |
4 - 1 | Monterrey |
... |
Jornada 11
| 22 Sep 21 | Monterrey |
1 - 0 | Toluca |
... |
| 28 Sep 21 | Atlas |
3 - 3 | Puebla |
... |
| 28 Sep 21 | Necaxa |
2 - 2 | Tijuana |
... |
| 28 Sep 21 | Mazatlán |
2 - 2 | Juárez |
... |
| 28 Sep 21 | Pachuca |
1 - 2 | América |
... |
| 29 Sep 21 | Querétaro |
1 - 2 | Chivas |
... |
| 29 Sep 21 | Atl. Luis |
2 - 1 | Tigres UANL |
... |
| 03 Nov 21 | Cruz Azul |
2 - 0 | León |
... |
| 04 Nov 21 | Pumas UNAM |
2 - 1 | Santos |
... |
Jornada 12
| 01 Oct 21 | Puebla |
1 - 1 | Pachuca |
... |
| 01 Oct 21 | Juárez |
1 - 0 | Monterrey |
... |
| 03 Oct 21 | América |
0 - 0 | Pumas UNAM |
... |
| 02 Oct 21 | Chivas |
0 - 2 | Atlas |
... |
| 02 Oct 21 | León |
2 - 0 | Atl. Luis |
... |
| 03 Oct 21 | Toluca |
2 - 0 | Querétaro |
... |
| 03 Oct 21 | Tigres UANL |
3 - 2 | Necaxa |
... |
| 02 Oct 21 | Santos |
4 - 2 | Mazatlán |
... |
| 04 Oct 21 | Tijuana |
0 - 1 | Cruz Azul |
... |
Jornada 13
| 14 Oct 21 | Querétaro |
3 - 3 | Tijuana |
... |
| 15 Oct 21 | Necaxa |
1 - 1 | Puebla |
1 |
| 15 Oct 21 | Mazatlán |
3 - 1 | Atlas |
... |
| 16 Oct 21 | Cruz Azul |
1 - 0 | Tigres UANL |
... |
| 16 Oct 21 | Monterrey |
1 - 1 | León |
... |
| 16 Oct 21 | Atl. Luis |
1 - 0 | América |
... |
| 16 Oct 21 | Pachuca |
2 - 2 | Santos |
... |
| 17 Oct 21 | Pumas UNAM |
3 - 0 | Juárez |
... |
| 17 Oct 21 | Chivas |
4 - 1 | Toluca |
... |
Jornada 14
| 21 Sep 21 | Juárez |
1 - 2 | Atl. Luis |
... |
| 15 Sep 21 | América |
0 - 1 | Santos |
... |
| 19 Oct 21 | Atlas |
0 - 0 | Cruz Azul |
... |
| 19 Oct 21 | Querétaro |
1 - 1 | Monterrey |
... |
| 19 Oct 21 | Puebla |
2 - 1 | Mazatlán |
... |
| 20 Oct 21 | Toluca |
0 - 1 | Necaxa |
... |
| 20 Oct 21 | León |
0 - 2 | Pumas UNAM |
... |
| 20 Oct 21 | Tigres UANL |
2 - 1 | Pachuca |
... |
| 21 Oct 21 | Tijuana |
1 - 2 | Chivas |
... |
Jornada 15
| 22 Oct 21 | Mazatlán |
4 - 0 | Querétaro |
... |
| 23 Oct 21 | América |
2 - 1 | Tigres UANL |
... |
| 23 Oct 21 | Chivas |
0 - 1 | Cruz Azul |
... |
| 23 Oct 21 | Puebla |
2 - 1 | León |
... |
| 23 Oct 21 | Monterrey |
5 - 1 | Necaxa |
1 |
| 24 Oct 21 | Pumas UNAM |
4 - 0 | Tijuana |
... |
| 24 Oct 21 | Atl. Luis |
0 - 2 | Atlas |
... |
| 24 Oct 21 | Santos |
3 - 0 | Toluca |
... |
| 25 Oct 21 | Pachuca |
6 - 0 | Juárez |
... |
Jornada 16
| 28 Oct 21 | Atlas |
1 - 1 | Tijuana |
... |
| 29 Oct 21 | Necaxa |
1 - 1 | Mazatlán |
... |
| 29 Oct 21 | Juárez |
1 - 1 | Puebla |
... |
| 30 Oct 21 | Querétaro |
0 - 5 | Santos |
... |
| 30 Oct 21 | Tigres UANL |
3 - 0 | Chivas |
... |
| 30 Oct 21 | Pachuca |
1 - 0 | Pumas UNAM |
... |
| 31 Oct 21 | Cruz Azul |
1 - 1 | América |
... |
| 31 Oct 21 | Toluca |
1 - 0 | León |
... |
| 31 Oct 21 | Atl. Luis |
3 - 1 | Monterrey |
... |
Jornada 17
| 04 Nov 21 | Atlas |
1 - 1 | Querétaro |
... |
| 05 Nov 21 | Puebla |
0 - 3 | Toluca |
... |
| 05 Nov 21 | Mazatlán |
1 - 0 | Chivas |
... |
| 06 Nov 21 | América |
2 - 0 | Monterrey |
... |
| 06 Nov 21 | Tigres UANL |
1 - 0 | Juárez |
... |
| 06 Nov 21 | León |
3 - 1 | Necaxa |
... |
| 10 Nov 21 | Tijuana |
2 - 1 | Pachuca |
... |
| 07 Nov 21 | Santos |
2 - 1 | Atl. Luis |
... |
| 07 Nov 21 | Pumas UNAM |
1 - 2 | Cruz Azul |
... |
