Jornada 1
| 20 Oct 18 |  Phoenix |
3 - 0 |  Portland |
9 |
| 20 Oct 18 |  Cincinnati |
1 - 1 |  Nashville |
4 |
| 20 Oct 18 |  Real |
0 - 1 |  Reno 1868 |
... |
| 21 Oct 18 |  Pittsburgh |
2 - 2 |  Philadelphi |
... |
| 21 Oct 18 |  Charleston |
0 - 1 |  York |
... |
| 21 Oct 18 |  Louisville |
4 - 1 |  Indy Eleven |
2 |
| 21 Oct 18 |  Orange |
4 - 0 |  Saint Louis |
... |
| 21 Oct 18 |  Sacramento |
1 - 2 |  Sporting |
10 |
Jornada 2
Jornada 3
Jornada 4
| 09 Nov 18 | Louisville |
1 - 0 | Phoenix |
22 |
Charleston Battery
Pittsburgh Riverhounds
Orange County SC
Sacramento Republic
Cincinnati
Phoenix Rising
Louisville City
Indy Eleven
Nashville SC
New York RB II
Real Monarchs
Sporting Kansas City II
Philadelphia Union II
Reno 1868
Saint Louis
Portland Timbers II